Cyclin A Antibody MBS438286 from MyBioSource.com

Product Specs
ItemCyclin A Antibody
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS438286
Quantity0.1 mg
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistology (IH)
Conjugate/TagUnconjugated
ReactivityHuman, Mouse, Cow, African Green Monkey, Mink (Mustela)
TargetCyclin A
IsotypeIgG2a kappa
Molecular Weight54kDa
CloneE67
HostMouse
ImmunogenIt recognizes a protein of 54kDa, which is identified as cyclin A. Its epitope is located amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk's) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk's. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase
NCBI Full Gene Namecyclin A2
NCBI Gene AliasesCCN1, CCNA
ClonalityMonoclonal